Let's start with the systems that DO support the 4-in-1:
Systems that DON'T support the 4-in-1:
Unfortunately, Wink doesn't support devices using multi-level command classes, like multisensors, regardless of brand.
Alarm panels like the ones listed above are closed systems with limited Z-Wave compatibility. They'll typically only work with single switches and relays, door locks, select thermostats, and any authorized devices on their official lists. They don't support multisensors, like the 4-in-1 Sensor, but you also won't be able to use other binary sensors with alarm panels, such as flood sensors, door/window sensors, and motion sensors.
Figuring out compatibility can be a pain so we try to be as transparent about it as possible, making sure all retail channels include that information in product descriptions as well. Let us know if you have any questions about your system!